Development and Validation of a Postoperative LEDVT Risk Assessment System for Severe Traumatic Brain Injury

严重创伤性脑损伤术后下肢深静脉血栓形成风险评估系统的开发与验证

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Abstract

OBJECTIVE: This study aimed to develop a structured risk assessment system for postoperative lower extremity deep vein thrombosis (LEDVT) in patients with severe traumatic brain injury (sTBI), and to validate its content and reliability through expert consensus. METHODS: The system was designed based on evidence from a comprehensive literature review and refined through a two-round Delphi expert consensus process involving 16 multidisciplinary experts. Indicator weights were assigned using an analytic hierarchy process combined with expert scoring. RESULTS: The finalized framework incorporated 6 primary domains-demographic characteristics, trauma-related indicators, coagulation parameters, comorbidities, iatrogenic factors, and venous thromboembolism prophylaxis-encompassing 19 secondary indicators. Response rates for two rounds of the expert questionnaire were 100%. The expert authority coefficient was 0.931. The coefficients of variation for the second-round indicators ranged from 0% to 7.01% and Kendall's coefficient of concordance was 0.670 (p < 0.001), indicating a high degree of expert agreement. CONCLUSION: A comprehensive risk prediction indicator system for LEDVT following sTBI surgery was established. The system is suitable for direct integration into hospital information systems, with weighted indicators reflecting clinical priorities and supporting the development of real-time monitoring modules.By enabling early identification of high-risk patients, this tool can facilitate timely prophylactic interventions, enhance clinical decision-making, and ultimately reduce the incidence of postoperative LEDVT, thereby improving patient safety and overall quality of care.

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