Feasibility of (18)F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography for the Assessment of Canine Granulosa Cell Tumours in Two Dogs

(18)F-氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在两只犬颗粒细胞瘤评估中的可行性

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Abstract

Two spayed female mongrels were presented for an abdominal mass and metastasis examination. To investigate suspected ovarian tumours and metastasis, (18)F-2-deoxy-2-fluoro-D-glucose ((18)F-FDG) positron emission tomography (PET)/computed tomography (CT) was performed. (18)F-FDG PET revealed mildly increased glucose uptake (maximum standardised uptake values, 2.03 and 1.32) without hypermetabolic invasion to adjacent tissue or lymphadenopathy. Histopathological examination confirmed that the excised ovarian tumours were granulosa cell tumours without angiolymphatic invasion. This is the first case report describing the feasibility of using (18)F-FDG PET/CT to detect canine granulosa cell tumours, highlighting their characteristics and identifying metastasis to regional lymph nodes or visceral organs.

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