Abstract
Cannabis hyperemesis syndrome (CHS) is a rare complication presenting with recurrent episodes of intractable nausea, vomiting, and abdominal pain that manifests in chronic cannabis use. Here, we report a case of a young male admitted to an inpatient psychiatric ward with drug-induced psychosis, who developed a cyclical vomiting illness on a background of long-term cannabis use. This case, characterised by recurrent emergency department presentations, weight loss, and medical complications, highlights the challenges associated with early recognition and diagnosis of CHS. We discuss the available literature on CHS and proposed management options. We highlight the difficulty of managing substance misuse-related pathologies with the stigma attached, and the importance of collaboration across various disciplines, whilst ensuring a holistic and multidisciplinary approach.