Abstract
Cholesterol emboli syndrome (CES) occurs when cholesterol crystals from atherosclerotic plaques embolize to distal arteries, often after invasive procedures like angioplasty. We report a 67-year-old man with hypertension, diabetes, and hyperlipidemia, who developed painful discoloration of his left toes following angioplasty for the management of myocardial infarction. Diagnosis of CES was confirmed by clinical findings, imaging, and a skin biopsy showing leukocytoclastic vasculitis. The patient was treated with anticoagulation, analgesics, and a vascular surgery consultation. This case underscores the importance of early recognition and management of CES to prevent further complications.