Quadriceps tendon-bone vs all soft-tissue autografts for primary anterior cruciate ligament reconstruction: a systematic review and meta-analysis of 7,748 patients

股四头肌腱-骨自体移植与所有软组织自体移植在原发性前交叉韧带重建中的比较:一项纳入7748例患者的系统评价和荟萃分析

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Abstract

PURPOSE: The purpose of this systematic review and meta-analysis was to synthesise available evidence on functional outcomes, knee stability, and complications between quadriceps tendon with patellar bone block (B-QT) and quadriceps soft-tissue (S-QT) autografts for primary anterior cruciate ligament reconstructions (ACLR). METHODS: A systematic search (PROSPERO ID: CRD42023472220) was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was performed on PubMed/MEDLINE, EMBASE, and WoS. The data concerning functional outcomes, knee stability, and complications were analysed. RESULTS: There were 5,898 B-QT patients (67.5% male) and 1,849 S-QT patients (51.5% male) included, with a mean age of 27.4 ± 9.3 and 24.7 ± 9.2 years and mean follow-up of 28.9 months (5.3-123.6 months) and 25.3 months (6.0-69.9 months), respectively. In a meta-analysis, the B-QT had higher KOOS subscales scores: activity-of-daily-living 95.98 (95% CI: 94.09-97.88) vs 93.88 (95% CI: 93.66-94.11), P = 0.028; pain 91.99 (95% CI: 89.48-94.49) vs 88.51 (95% CI: 88.21-88.81), P = 0.005; sports & recreation 84.26 (95% CI: 79.20-89.31) vs 79.21 (95% CI: 78.69-79.73), P = 0.041; symptoms 87.82 (95% CI: 84.75-90.90) vs 81.26 (95% CI: 80.71-81.82), P < 0.001; quality-of-life 78.28 (95% CI: 73.68-82.89) vs 65.37 (95% CI: 60.59-70.15), P < 0.001; and a higher Marx score: 11.90 (95% CI: 10.92-12.87) vs 9.65 (95% CI: 8.21-11.09), P = 0.006. B-QT had higher side-to-side difference in anteroposterior tibial translation: 1.55 mm (95% CI: 1.33-1.77) vs 1.15 mm (95% CI: 0.85-1.33 mm), P = 0.026. CONCLUSION: A QT autograft, with or without a bone block, provides satisfactory functional outcomes, knee stability, and few complications in primary ACLR. B-QT may result in higher patient-reported outcomes, while S-QT may potentially result in slightly improved knee stability.

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