Abstract
RATIONALE: Aortic stenosis (AS) is currently the most frequent valve disorder. In addition, the angiodysplasias are the most common vascular malformations of the gastrointestinal tract. Heyde syndrome (HS) is a rare disease which links these 2 pathological conditions. PATIENT CONCERNS: Currently, there are no clearly defined guidelines for the confirmation of HS diagnosis and for timing of aortic valve replacement in patients with confirmed HS, despite the fact that HS is connected with increased mortality and the need for numerous rehospitalizations and multiple blood transfusions. Therefore, the aim of this study was to report (our) first experiences with novel diagnostic method for acquired von Willebrand (vW) syndrome and transcatheter aortic valve replacement (TAVR) for treatment of HS. DIAGNOSES: We report a case of a 68-year-old man who was diagnosed with HS with the use of semiautomatic vW factor multimer analysis. INTERVENTIONS: A successful TAVR was used for treatment of AS. OUTCOMES: After the interventional treatment of AS, the patient did not have a recurrence of the anemic syndrome. LESSONS: This is a unique case of a patient with HS in whom semiautomatic vW factor multimer analysis was used for diagnosis of acquired vW syndrome together with TAVR procedure for HS treatment.