[Retracted] Upregulation of Stat1‑HDAC4 confers resistance to etoposide through enhanced multidrug resistance 1 expression in human A549 lung cancer cells

[已撤稿] Stat1-HDAC4 的上调通过增强人 A549 肺癌细胞中多药耐药蛋白 1 的表达赋予其对依托泊苷的耐药性

阅读:1

Abstract

Following the publication of this article, an interested reader drew to the Editor's attention that a pair of data panels in the cellular images shown in Fig. 1A on p. 2317 appeared to be overlapping, such that data which were intended to show the results from differently performed experiments had appparently been derived from the same original source. Moreover, in Fig. 1C and 5A, there appeared to be discrete splicing events for gel slices featured in these figure parts, and for the immunoblotting experiments shown in Fig. 2B, striking likenesses of certain of the bands appeared in different positions in different gels relative to each other where different experimental conditions were being shown, which seemed difficult to attribute purely to coincidence. After having conducted an internal investigation, the Editor of Molecular Medicine Reports agrees with the reader that there were anomalies associated with the presentation of Figs. 1, 2 and 5. Therefore, on the grounds of a lack of confidence in the presented data, the Editor has decided that the article should be retracted from the publication. Upon contacting the authors, all the authors agreed with the decision to retract this paper, except for Dr Randal Johnston, who was not contactable owing to his retirement several years ago. The Editor apologizes to the readership for any inconvenience caused, and we also thank the reader for bringing this matter to our attention. [Molecular Medicine Reports 11: 2315‑2321, 2015; DOI: 10.3892/mmr.2014.2949].

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。