Short-term outcomes of treatment for ruptured intracranial aneurysms using flow diverter and coiling: A single-center experience

采用血流导向装置和弹簧圈栓塞术治疗破裂性颅内动脉瘤的短期疗效:单中心经验

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Abstract

The safety and feasibility of treating ruptured intracranial aneurysms with flow diverter (FD) deployment and coiling were evaluated in this study. The Hunt-Hess (HH) scale score was used to assess preoperative status in patients. Before endovascular treatment, a loading dose of aspirin and ticagrelor was administered. The Raymond-Roy classification (RRC) was applied to evaluate aneurysm occlusion grades. Follow-up outcomes were assessed using modified Rankin scale analysis and RRC grading. Fifty-two patients aged 57 ± 8.8 years with intracranial hemorrhage were enrolled. There were 53 aneurysms among 52 patients. After treatment with FD and coiling, immediate RRC occlusion grades were 1, 2, and 3 for 21 (39.6%, 21/53), 21 (39.6%, 21/53), and 11 (20.8%, 11/53) aneurysms, respectively. Among 52 patients, complications occurred in 21.2% (11/52), with 4 fatalities: 1 HH 3 and 1 HH 4 (vasospasm), 1 HH 3 (heart failure), and 1 HH 4 (pneumonia). Among the 48 surviving patients, follow-up modified Rankin scale scores were distributed as follows: 43 (89.6%, 43/48) with score 0, 3 (6.3%, 3/48) with score 1, 1 (2.1%, 1/48) with score 2, and 1 (2.1%, 1/48) with score 3. Forty-two patients with 42 aneurysms underwent follow-up angiography, revealing RRC occlusion grade 1 in 39 aneurysms and grade 2 in 3 aneurysms. In conclusion, endovascular treatment of ruptured aneurysms with FD and coiling demonstrates feasibility; however, severe complications-especially in patients with high HH scale scores-necessitate cautious evaluation.

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