Parker Mobility Score as a Screening Tool for Sarcopenia in Older German Adults: A Cross-Sectional Analysis of Trial Data

Parker活动能力评分作为德国老年人肌少症筛查工具:一项横断面试验数据分析

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Abstract

BACKGROUND: Sarcopenia is the pathologic loss of muscle strength and mass. SARC-F screener for sarcopenia has been criticized for its low sensitivity. The Parker Mobility Score (PMS) is widely used to assess mobility in older adults. This study evaluates PMS's ability to detect sarcopenia. METHODS: We used data from the Paint II clinical trial, which examined the effects of art therapy in community-dwelling older individuals. Sarcopenia was defined using EWGSOP2 criteria: probable sarcopenia as handgrip strength < 27 kg (men) or < 16 kg (women) and/or chair stand test > 15 s. Sarcopenia was confirmed in patients with probable sarcopenia when their appendicular skeletal muscle mass index was below 7 kg/m² for men or 5.5 kg/m² for women. The PMS's diagnostic performance was assessed using ROC analysis. RESULTS: Data from 255 participants (200 (78%) female, median age 81) were analyzed. 196 (77%) participants had probable sarcopenia and 26 (10%) were sarcopenic. PMS showed moderate discrimination for probable sarcopenia, with an AUC of 0.75 (95% CI: 0.68-0.81). The cutoff (< 8) provided a sensitivity of (77%) and specificity of (64%). For sarcopenia, the AUC was 0.61 (95% CI: 0.52-0.69), indicating low to moderate discrimination. The PMS cutoff of < 8 showed high sensitivity (92%), but low specificity (36%). Similar results were observed for sarcopenic obesity, with an AUC of 0.61. CONCLUSION: PMS demonstrated moderate accuracy for identifying probable sarcopenia and high sensitivity for detecting sarcopenia. Although this high sensitivity is linked to a lower specificity, the trade-off is acceptable because the follow-up diagnostic tests are non-invasive with low costs. Due to its widespread use and feasibility in clinical practice, PMS may represent a practical tool for case finding. Further research is required to confirm its accuracy in different populations.

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