Functional and quality of life outcomes following surgical treatment for cauda equina syndrome: A retrospective tertiary centre study

马尾综合征手术治疗后的功能和生活质量结果:一项回顾性三级中心研究

阅读:1

Abstract

BACKGROUND: This study evaluated bladder, bowel, and sexual function outcomes following surgical decompression for cauda equina syndrome (CES) using urodynamic studies (UDS) and patient-reported outcome measures (PROMs), and explored the influence of surgical timing on recovery. Evidence integrating objective UDS findings with PROMs remains limited. METHODS: Forty-five patients with clinically and radiologically confirmed CES who underwent decompression were analysed retrospectively. Functional outcomes were evaluated using the Neurogenic Bowel Dysfunction Score (NBDS), Urinary Symptom Profile (USP), Arizona Sexual Experience Scale (ASEX), and SF-12. Surgical timing was analysed as a continuous variable and stratified into <24 h, 24-36 h, and >36 h. Thirty-six patients had long-term postoperative urodynamic data, while a subset of nine patients had both pre- and postoperative assessments. Final urodynamic patterns were analysed as cross-sectional functional outcomes across the entire cohort, while longitudinal changes in the subset were analysed separately as exploratory findings. RESULTS: Median age was 39 years; 71% were male. Lumbar disc herniation accounted for 87% of cases. In an exploratory subset (n = 9), 78% demonstrated improvement in urodynamic patterns at three months, with 22% achieving normal voiding. At final follow-up, 61% demonstrated contractile bladder activity. NBDS correlated significantly with UDS findings (ρ = 0.41, p = 0.02). Sexual dysfunction was observed in 67% of early postoperative and 22% of long-term patients. A higher proportion of contractile recovery was observed with earlier surgery, although this did not reach statistical significance (p = 0.16). CONCLUSIONS: Surgical decompression for CES leads to meaningful but often incomplete bladder recovery. A non-significant trend toward improved outcomes with earlier intervention was observed; however, causal inference is limited by the study design. Integration of UDS with PROMs provides a comprehensive assessment of recovery and should be incorporated into routine follow-up.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。