Abstract
The 2025 HTAi Global Policy Forum (GPF) report offers a timely and thoughtful synthesis of the opportunities and challenges associated with the use of artificial intelligence (AI), and particularly generative AI (GenAI), in Health Technology Assessment (HTA) (1). Its emphasis on trust, human agency, and risk-based approaches reflects both the maturity of the discussion within the HTA community and a shared recognition that technical capability alone is insufficient for responsible adoption. The report succeeds in articulating a common set of principles and a broadly aligned vision across HTA bodies, life sciences, and other interest holders.