Deformable Fricke-XO-Gelatin Radiochromic Dosimeter of Ionizing Radiation and Its Applications in Quality Assurance Tests for Radiation Therapy

可变形弗里克-XO-明胶放射变色电离辐射剂量计及其在放射治疗质量保证测试中的应用

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Abstract

This work presents a Fricke radiochromic gel dosimeter with xylenol orange (XO) and a gelatin matrix modified with sorbitol. The dosimeter, combined with 2D scanning using a flatbed scanner and data processing using dedicated software packages, creates a radiotherapy dosimetry measurement system. The dosimeter reacts to ionizing radiation by changing color as a result of the formation of complexes of Fe(3+) and XO molecules. It was characterized in terms of thermal and chemical stability and mechanical properties. The presence of sorbitol improved the mechanical and thermal properties of the dosimeter. The dosimeter maintains chemical stability, enabling its use in dosimetric applications, for at least six weeks. The dose-response characteristics of the dosimeter are discussed and indicate a dynamic dose-response of the dosimeter (up to saturation) of about 20 Gy and a linear dose-response of about 12.5 Gy. The following applications of the dosimeter are discussed: (i) as a 2D dosimeter in a plastic container for performing a coincidence test of radiation and mechanical isocenters of a medical accelerator, and (ii) for in vivo dosimetry as a 2D dosimeter alone and simultaneously as a bolus and a 2D dosimeter. Research has shown that the dosimeter has promise in many applications.

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