Correction: Circulating senescence-associated secretory phenotype factors across the stages of type 1 diabetes in a cross-sectional cohort

更正:横断面队列研究中 1 型糖尿病各阶段循环衰老相关分泌表型因子

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Abstract

Long-term cold exposure reduces livestock welfare and productivity in Inner Mongolia. This study assessed cold stress effects on 60 two-month-old female Dorper × Mongolia lambs allocated to four sheltering conditions (n = 15): indoor pens with enclosed housing (IP), outdoor pens (OP), house with playground pens (OPP), and polytunnel pens (PP). Compared with IP, OP exhibited significantly lower temperature, humidity, CO(2) concentration, NH(3) concentration, and WCI, and significantly higher wind speed and solar radiant heat (p < 0.001). Humidity, CO(2) concentration, and NH(3) concentration in PP was lower than in IP, but higher than in OP (p < 0.001); temperature, wind speed, and WCI did not differ significantly between PP and IP. ADG was significantly lower in OP and OPP than in IP (p < 0.001), whereas PP did not differ from IP. F:G was higher in OP than in IP and PP (p = 0.040). Feeding duration had significant effects on ACTH, leptin, T(3), T(4), TP, urea, TG, NEFA, LDL, and HDL concentrations. Rearing environment significantly affected GLU, ALB, LDH, and TG. Feeding duration × sheltering conditions interaction significantly influenced ACTH, TP, ALB, urea, LDH, TG, LDL, and HDL. OP induced cold stress and dysfunction, while IP and PP produced milder responses. PP raised indoor temperatures substantially, and is thus optimal for winter lamb production.

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