A Case Report of a Patient Presenting With Extra-skeletal Myxoid Chondrosarcoma

一例骨外黏液样软骨肉瘤病例报告

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Abstract

Extra-skeletal myxoid chondrosarcoma (EMC) is a type of rare sarcoma of uncertain differentiation. This malignancy is marked by the growth of primitive chondroid cells forming multiple nodules within a rich myxoid matrix. It is distinguished by a specific translocation resulting in the fusion gene EWSR1::NR4A3, which is a distinctive molecular hallmark of EMC. EMC is categorised as an intermediate-grade tumour and is distinguished by a prolonged clinical course with a high likelihood of local recurrence and distant metastasis. Surgical treatment is the only option for a cure for EMC, while non-surgical treatments are typically considered for recurrent or distant disease. This case report discusses an interesting case of a patient with EMC and further elaborates on the history, examination, imaging, pathological findings, and management of EMC.

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