Single-neuron spiking variability in hippocampus dynamically tracks sensory content during memory formation in humans

人类海马体中单神经元放电变异性动态地跟踪记忆形成过程中的感觉内容。

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Abstract

During memory formation, the hippocampus is presumed to represent the content of stimuli, but how it does so is unknown. Using computational modelling and human single-neuron recordings, we show that the more precisely hippocampal spiking variability tracks the composite features of each individual stimulus, the better those stimuli are later remembered. We propose that moment-to-moment spiking variability may provide a new window into how the hippocampus constructs memories from the building blocks of our sensory world.

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