Efficacy and safety of radiofrequency ablation combined with high ligation vs simple radiofrequency ablation for lower extremity varicose veins: a retrospective comparative study

射频消融联合高位结扎术与单纯射频消融治疗下肢静脉曲张的疗效和安全性:一项回顾性比较研究

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Abstract

INTRODUCTION: Simple radiofrequency ablation (RFA) is a standard minimally-invasive treatment for lower extremity varicose veins (LEVV), yet concerns regarding recurrence and efficacy in severe cases persist. AIM: We aimed to evaluate clinical efficacy, safety, and long-term prognosis of RFA combined with high ligation (RFHL) vs simple RFA. MATERIALS AND METHODS: This retrospective study analyzed 108 LEVV patients (from January 2020 to November 2024) divided into 2 groups based on the procedure they underwent: RFHL (n = 54) and RFA (n = 54). The comparisons included perioperative indicators, clinical efficacy, complications, and 1-year recurrence rates. A stratified analysis was performed for severe cases (Clinical-Etiology-Anatomy-Pathophysiology [CEAP] classification, C4-C6). RESULTS: Perioperative metrics (operative time, blood loss, recovery, and pain intensity) showed no differences between the groups. However, RFHL achieved a significantly higher total effective rate than RFA. Notably, in severe cases (C4-C6), RFHL efficacy was superior. The RFHL group demonstrated markedly lower complication and 1-year recurrence rates. Additionally, 6-month venous function was considerably better in the RFHL group. CONCLUSIONS: RFHL is associated with comparable perioperative recovery to RFA but offers significantly higher efficacy, better safety, and lower long-term recurrence, especially in severe LEVV (CEAP, C4-C6). RFHL should be considered the preferred surgical approach for severe cases.

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