Management of Moderate-to-Highly Exuding Chronic Leg Ulcers With Superabsorbent Wound Dressings Versus Foams Dressings in Polish Settings: An Early-Stage Cost-Effectiveness Evaluation

在波兰,使用超吸收性伤口敷料与泡沫敷料治疗中重度渗出性慢性腿部溃疡的早期成本效益评估

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Abstract

INTRODUCTION: Chronic leg ulcers (CLUs) are complex wounds that often fail to heal within a reasonable timeframe, leading to prolonged morbidity, reduced quality of life and significant healthcare costs. The severity and exudate level of these wounds influence treatment choice and patient outcomes. In Poland, evidence on the economic impact of advanced dressings for CLUs remains limited, despite their inclusion in clinical guidelines. AIM: This study aims to evaluate the cost-effectiveness and cost-utility of superabsorbent polymer dressings versus foam dressings in the management of moderate-to-highly exuding chronic leg ulcers within Polish healthcare settings. METHODS: This early-stage model-based economic evaluation was conducted in a time horizon of 6 months within the context of the Polish healthcare system. The model inputs were identified through systematic literature reviews and incorporated into a mathematical model that accounted for the natural history of chronic leg ulcers. RESULTS: The average cost per patient for superabsorbent polymer dressings was estimated at PLN 11144 (€2563; $2786), while foam dressings averaged PLN 14685 (€3378; $3671), contributing to the cost difference between the two wound dressings of PLN 3541 (€815; $885) per patient over 6 months. Healing rates are projected to improve by an additional 2%, and health-related quality of life is expected to increase by 0.123 quality-adjusted life weeks in favour of superabsorbent polymer dressings. CONCLUSION: These results provide evidence that superabsorbent polymer dressings are clinically and economically viable treatment options compared to foams for moderately to excessively exuding chronic leg ulcers in Poland.

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