Abstract
Stress urinary incontinence (SUI) is a prevalent condition characterized by involuntary urine leakage during physical activities. This condition can significantly impact a woman's quality of life. Treatment options for SUI include behavioral therapy, medication, and surgery. However, non-pharmacological methods such as low-level laser therapy (LLT) have demonstrated the potential to promote tissue repair, reduce inflammation, and improve pelvic floor muscle function in various pelvic floor disorders. Despite these benefits, the effectiveness of combined transvaginal and intra-bladder LLT for managing SUI has not been extensively studied. This case series aimed to assess the safety and efficacy of a novel regimen using concurrent transvaginal and intra-bladder LLT for the treatment of stress urinary incontinence in perimenopausal and postmenopausal women. The results appear promising, and further investigation is recommended. Trial Registration: This clinical trial was registered in the Iranian Registry of Clinical Trials (IRCT) under the registration number IRCT20231203060255N2, on 30 June 2024 (retrospectively registered).