Abstract
Ovarian cancer represents a major public health problem. It is the deadliest gynecological cancer with a high metastatic potential. Unilateral axillary lymph node metastases are rarely seen in ovarian cancer, and bilateral lymph node metastases are exceptional. We report a case of a 61-year-old female patient presenting with bilateral axillary lymphadenopathy secondary to high-grade serous carcinoma of the right ovary. Treatment consisted of lymph node excision, adnexectomy, cytoreduction, and chemotherapy. Diagnostic, therapeutic, and prognostic aspects are discussed through a literature review. The axillary localization of ovarian cancer, although rare, can be observed, especially in the postmenopausal period. Treatment is based on cytoreductive surgery but can be supplemented by neoadjuvant chemotherapy.