Contrast-Enhanced Magnetic Resonance Imaging (MRI) as a Prognosticator for the Conservative Treatment of Lumbar Disc Prolapse: A Prospective Observational Study

对比增强磁共振成像(MRI)作为腰椎间盘突出保守治疗预后的预测指标:一项前瞻性观察研究

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Abstract

INTRODUCTION: Lumbar disc herniation (LDH) is a common spinal pathology, often managed conservatively. However, predicting which patients will show spontaneous resolution versus persistent symptoms remains a clinical challenge. This study aims to evaluate the role of contrast-enhanced magnetic resonance imaging (MRI) in predicting the natural history of disc prolapse and correlating it with clinical improvement.  Materials and methods: A prospective observational study was conducted involving 50 patients between the ages of 18 and 65 years who have been undergoing treatment for the primary diagnosis of LDH. Patients were enrolled if they have partial relief of symptoms at the end of 6-8 weeks of conservative trial. All participants underwent contrast-enhanced MRI to evaluate the presence of rim enhancement. A clinico-radiological correlation was performed based on whether or not rim enhancement was observed on the contrast-enhanced MRI.  Results: Among the 44 patients who had contrast enhancement on MRI, 42 patients (95.5%) showed a good clinical outcome at the time of final follow-up as measured by the visual analog scale (VAS) score. Among the total group, six patients (12%) required a surgical procedure for relief of their symptoms, and the majority of these patients, four out of six (66.7%), were those who had failed conservative management without any contrast enhancement on MRI. CONCLUSION: Contrast-enhanced MRI can serve as a powerful diagnostic adjunct in patients with incomplete symptom resolution during the conservative management of LDH. The presence of peripheral rim enhancement may predict favorable spontaneous resolution, enabling clinicians to make informed decisions regarding continued non-operative treatment versus surgical referral.

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