Feasibility study of subject-specific, brain specific-absorption-rate maps retrieved from MRI data

利用MRI数据获取个体特异性脑吸收率图的可行性研究

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Abstract

INTRODUCTION: Specific absorption rate (SAR) is crucial for monitoring radiofrequency power absorption during MRI. Although local SAR distribution is usually calculated through numerical simulations, they are impractical during exams, limiting real-time patient-specific SAR assessment. This study confirms the feasibility of deriving in vivo, subject-specific, image-based SAR and 10-g SAR maps directly from MRI data. METHODS: Complex B(1) (+) maps were derived by combining a B(1) (+) product (XFL) magnitude sequence with balanced steady-state free precession phase. Anatomical information and tissue masking were obtained from a T(1) magnetization-prepared rapid gradient echo sequence. Electrical conductivity maps were generated from balanced steady-state free precession phase. Whole-brain SAR maps were created from MRI data acquired at 3 T using a 32-channel head coil on 2 healthy volunteers. A correction factor was applied to account for underestimation due to reliance on measurable B(1) (+) data. Numerical simulations compared image-based SAR with simulation-based SAR distributions. RESULTS: A multi-slice image-based brain SAR map was obtained in 12 min (9-min acquisition, 3-min SAR reconstruction). In vitro experiments validated B(1) (+) distribution and electrical conductivity values. Calculated electrical conductivities for in vitro and in vivo experiments were within reference ranges. Image-based SAR and 10-g SAR maps showed a distribution similar to simulation-based maps (r = 0.5) after correction. CONCLUSIONS: This study shows the feasibility of inline, subject-specific SAR and 10-g SAR maps from standard brain clinical sequences. Image-based SAR maps can be a practical alternative during MRI exams when simulations are not feasible.

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