Abstract
Background: Artificial Intelligence (AI) is transforming healthcare education, offering innovative tools to enhance learning and clinical decision-making. AI-driven platforms like ChatGPT are increasingly integrated into pharmacy education, enabling students to access vast medical knowledge, refine decision-making skills, and simulate clinical scenarios. Objective: This study examines pharmacy students' attitudes, knowledge, and practices regarding ChatGPT's use in clinical decision-making, evaluates its perceived benefits and limitations, and identifies factors influencing AI integration in pharmacy education. Methodology: A cross-sectional study was conducted among 512 pharmacy students at King Khalid University. A structured questionnaire assessed demographics, knowledge, attitudes, and practices. Data were analyzed using SPSS, employing descriptive statistics, chi-square tests, and logistic regression. Results: The majority (82.4%) supported AI integration in pharmacy education, while 74.6% believed that ChatGPT could enhance clinical decision-making. Primary applications included drug information retrieval (72.3%) and exam preparation (66.7%). However, concerns about AI accuracy (55.2%) and ethical implications were noted. Conclusions: Pharmacy students at King Khalid University exhibit positive attitudes toward AI, recognizing its educational benefits while acknowledging challenges. Addressing accuracy concerns and ethical considerations through structured AI training programs is essential to optimize AI's role in pharmacy education and practice.