Abstract
Lactococcus garvieae, a Gram-positive bacterium traditionally associated with infections in fish, has been increasingly recognized as a rare pathogen in human infections, including urinary tract infections (UTIs). We present a case of a 75-year-old male patient with pyohydronephrosis and a complex medical history who was diagnosed with a UTI caused by L. garvieae. The patient was successfully treated with a combination of intravenous ampicillin/sulbactam followed by oral linezolid, resulting in the resolution of symptoms. This report also compares this case with other documented cases of L. garvieae infections, highlighting its pathogenic mechanisms, clinical manifestations, treatment strategies, and the need for heightened awareness of this pathogen.