Refractory Bleeding From an Ileal Conduit in a Patient With Antiphospholipid Syndrome: A Multidisciplinary Management Challenge

Bleeding from an ileal conduit is a rare but potentially life-threatening complication, typically associated with portal hypertension and stomal varices. However, intra-conduit hemorrhage in benign settings is exceedingly rare. We report a case of a 54-year-old woman with a complex history including antiphospholipid syndrome (APS), who presented with persistent bleeding from an ileal conduit, ultimately requiring multidisciplinary intervention after failed conservative management. This case illustrates the challenges of balancing anticoagulation in high thrombotic risk patients and the importance of timely escalation to specialist care.