Abstract
Mucormycosis is an opportunistic fungal infection that severely impacts immunocompromised patients. Invasive mucormycosis tends to require surgical procedures like maxillectomy, leading to a complex oro-nasal communication and a severe compromise of oral function, speech, and esthetics. The following case report describes the prosthetic rehabilitation of a patient after maxillectomy post-mucormycosis. A maxillary complete denture with a closed hollow bulb obturator was constructed to restore oral function, facilitate speech, and improve facial esthetics. The impression-making technique was meticulously altered to obtain a precise recording of the defect, and a new flasking technique was used during processing to create a lightweight yet retentive prosthesis. Thermocol was strategically utilized to hollow the obturator and alveolar ridge segments, thereby reducing the weight while preserving structural support. Soft relining with Molloplast B (Detax GmbH & Co. KG, Ettlingen, Germany) was performed to enhance mucosal adaptation as well as patient comfort. After-insertion assessment indicated optimal fit, retention, and patient satisfaction, with marked improvement in speech and mastication. Follow-up at regular intervals showed maintained function and comfort, underlining the critical role of prosthodontic rehabilitation in the interdisciplinary management of post-mucormycosis maxillary defects.