Abstract
Gastrointestinal stromal tumors (GISTs) are rare small intestinal tumors. Due to challenging diagnoses, the majority of patients typically report chronic problems. Early diagnosis and the start of appropriate treatment depend on high suspicion. We present a case of a 47-year-old male patient who first experienced fever, nausea, vomiting, and pain in the right upper quadrant. Radiologic examinations showed an intra-abdominal tumor containing oral contrast and a liver lesion, indicating gastrointestinal tract involvement. He had an ileal GIST that created a fistula between the tumor and the small intestine, complicated by a liver abscess. We surgically removed the tumor and intra-operatively drained the liver abscess. A liver lesion found in conjunction with a small intestine GIST should cause concern for both the possibility of infectious complications such as a pyogenic liver abscess and metastatic illness. The uncommon appearance of an ileal GIST with a tumor-intestinal fistula, accompanied by a liver abscess, is reviewed in this case report.