Abstract
The incidence of cancer is dramatically increasing worldwide. Renal cell carcinoma (RCC) accounts for approximately 4% of new cancer diagnosis each year and about 2% of deaths due to cancer. With its unique property of tumor thrombus formation and extension into the blood vessels, RCC with tumor thrombus necessitates a multidisciplinary approach for prompt diagnosis and surgical management of such patients. We present a series of six cases of RCC with tumor thrombus in the inferior vena cava (IVC) operated between April 2009 and April 2025, at various levels of extension and its surgical management. Three cases were performed with the assistance of sternotomy and the institution of cardiopulmonary bypass (CPB); the other three cases required local resection, without CPB. We had one intra-operative mortality. The follow-up period ranged between 40 and 188 months, with a mean follow-up period of 98.8 months, and our results are matching the previous studies. We would like to highlight the importance of close coordination amongst various disciplines in formulating a plan for successful surgical management of this subset of patients that can positively influence the survival rates.