Abstract
This study assesses nursing students' attitudes toward artificial intelligence (AI) and examines the role of personality traits in shaping these attitudes. Methods: A cross-sectional study was conducted in which 159 nursing students from the University of Thessaly participated. Data were collected using the General Attitudes Toward Artificial Intelligence Scale (GAAIS) to measure attitudes toward AI and the Ten Item Personality Inventory (TIPI) to assess personality traits. Statistical analysis included descriptive and inferential methods, such as correlation and factor analysis. The significant level was set to p<0.05. Results: The findings revealed moderately positive attitudes toward AI (mean positive attitude score: 3.22 out of 5). Extraversion and openness to experience were positively correlated with positive attitudes, while maternal education was significantly associated with lower negative attitudes. Conclusion: Nursing students demonstrate a cautious optimism toward AI, with personality traits and education playing a key role in shaping their perceptions. Addressing concerns about AI through targeted educational programs could enhance students' confidence and willingness to adopt AI in their professional practice. These findings emphasize the importance of integrating AI into nursing curricula to bridge knowledge gaps and promote the effective use of AI technologies in healthcare.