Abstract
BACKGROUND: Tuberculosis control in Tasikmalaya relies on competent drug supervisors (DS) to ensure adherence, yet knowledge gaps remain. OBJECTIVES: To assess factors influencing DS effectiveness in Tasikmalaya, Indonesia. METHODS: A cross-sectional study of 121 DS was conducted. Data on sociodemographic factors, knowledge, attitudes, and practices were collected through validated questionnaires. Logistic regression was used to identify determinants of DS performance. RESULTS: Female and officially designated DS were significantly more effective in ensuring adherence compared to males and voluntary DS. Overall knowledge was inadequate among most DS (95.9%). Cadres performed better than family members in supervisory tasks. CONCLUSION: Improving DS capacity-especially family and male supervisors-through structured training and official designation can enhance TB treatment outcomes.