Immune Checkpoint Inhibitor-Mediated Aseptic Meningitis and Hypophysitis

免疫检查点抑制剂介导的无菌性脑膜炎和垂体炎

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Abstract

Immune checkpoint inhibitors have revolutionized cancer treatment, yet their use is associated with unique and sometimes unpredictable immune-related adverse events. We present a case of a 67-year-old female with renal cell cancer treated with ipilimumab and nivolumab who developed aseptic meningitis and hypophysitis. This case highlights the challenges in managing immune-related adverse events and underscores the need for vigilance in monitoring patients receiving ICIs.

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