Assessment of selective salivary properties and taste perception in subjects with oral submucous fibrosis - A case-control study

口腔黏膜下纤维化患者选择性唾液特性和味觉感知的评估——一项病例对照研究

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Abstract

BACKGROUND: The present study was conducted to evaluate and compare selective salivary properties and taste perception in subjects with and without oral submucous fibrosis (OSMF), since OSMF affects the properties of saliva and may lead to decline in the quality of life. MATERIALS AND METHOD: Eighty subjects were enrolled in the study and equally divided into two groups based on the presence or absence of OSMF, for estimating, analysing and comparing the salivary flow rate (SFR), pH and taste perception using Modified Schirmer strip, pH strip and taste solutions respectively, in both groups. Chi-square test and unpaired t-test were applied. RESULTS: Compared to the control group, a statistically significant decrease in SFR was noted among stage 4 OSMF subjects. Alkaline pH was present in OSMF group, regardless of the stage. Taste alterations were present in relation to sweet, salty and sour taste in subjects with OSMF. CONCLUSION: There is a marked decrease in SFR, alteration in salivary pH and significant taste changes such as hypogeusia, dysgeusia and ageusia in sweet, salt and sour tastes in subjects with OSMF.

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