Abstract
Fetal type adenocarcinoma (FTA) is a rare malignant tumor of the lung that histologically resembles an embryonic lung. Due to its rarity, no studies had investigated the possible role of the (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ([(18)F]FDG PET/CT) in the initial assessment and/or in the restaging of the disease yet. We present a case of a male patient with tongue carcinoma and incidental findings of well-differentiated FTA at [(18)F]FDG PET/CT. The patient was treated by specific therapy and also performed a subsequent [(18)F]FDG PET/CT scan that showed a significant reduction of the uptake on lung lesion. This case highlights the potential role and usefulness of PET imaging for staging and posttherapeutic restaging of well-differentiated FTA. The review of the available literature underlined the rarity of the disease since only seven reports were present. Anyway, a possible role of the [(18)F]FDG PET/CT in the staging of FTA is conceivable.