Abstract
We report a rare case of adenosquamous carcinoma of the gallbladder. The patient presented with unexplained weight loss and a palpable mass below the right costal margin. A computed tomography (CT) scan suggested gallbladder carcinoma, prompting radical surgery. Histological assessment confirmed adenosquamous carcinoma of the gallbladder. Although resection margins were negative (R0), peritumoral lymph node metastases were identified. The patient subsequently received adjuvant chemotherapy with capecitabine, as recommended by a multidisciplinary tumor board (MDT). Six-month follow-up imaging showed no evidence of metastasis or recurrence.