Abstract
Currently, photodynamic therapy (PDT) is widely used, mainly in treatment of actinic keratosis (AK), especially grades I and II following the Olsen classification. The main side effects include burning, stinging, and pain during irradiation. Alternative protocols include daylight PDT (dPDT), which uses sunlight instead of artificial light after applying a photosensitizer. Unlike conventional PDT, daylight therapy is less painful and more comfortable for patients. This article presents the mechanism of dPDT, indications for this method as well as its efficiency, side effects, advantages and disadvantages. In the end, current treatment protocols of dPDT are presented.