Abstract
Chronic myeloproliferative neoplasms（MPNs）are a group of acquired malignant tumors characterized by clonal proliferation of hematopoietic stem cells, among which polycythemia vera, essential thrombocythemia, and primary myelofibrosis are known as the classical Philadelphia chromosome-negative MPN. Hypertension is the most common complication in patients with MPN and has a significant effect on the clinical presentation, disease progression, treatment, and prognosis of patients with MPN. However, it may not have received sufficient attention from hematologists in clinical practice. This article reviews the epidemiology and clinical issues of patients with MPN and comorbid hypertension to assist clinicians in providing individualized treatment for these patients.