Oral Eplerenone for Exudative Retinal Detachment Secondary to Central Serous Chorioretinopathy: A Case Report

口服依普利酮治疗中心性浆液性脉络膜视网膜病变继发渗出性视网膜脱离:病例报告

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Abstract

Central serous chorioretinopathy (CSCR) is a retinal disorder characterized by subretinal fluid (SRF) accumulation, and its bullous variant represents a rare and severe form often lacking standardized treatment. We report a case of a patient with short stature and normal cortisol and growth hormone levels, diagnosed with the bullous variant of CSCR and treated with oral spironolactone, a mineralocorticoid receptor (MR) antagonist. The patient showed marked resolution of exudative retinal detachment (RD) and improvement in visual acuity within one month of initiating therapy with 50 mg/day of spironolactone. This case highlights the potential role of oral spironolactone as an effective and less invasive therapeutic option for managing the bullous variant of CSCR, offering a promising alternative to more aggressive interventions.

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