Abstract
Lipomas are benign tumours derived from adipocytes, commonly found across the body, especially on the trunk and limbs. Although typically small, rare cases involve giant lipomas larger than 10 cm, often causing clinical symptoms. We report a case of a giant parietal peritoneal lipoma in a 45-year-old obese woman presenting with right upper abdominal pain. Imaging revealed a large, well-defined fatty mass in the abdominal wall, which was surgically excised laparoscopically. The specimen measured 18x14 cm and weighed 984 gm, with histology confirming a benign lipoma. The procedure was uncomplicated, with the patient discharged on day five and no recurrence over two years of follow-up. Only seven similar giant abdominal wall lipomas have been documented, with just one treated laparoscopically before. This case highlights the effectiveness and minimally invasive benefits of laparoscopic excision for large abdominal wall lipomas, which are rare but can present with symptoms mimicking other conditions.