A Service Evaluation of Antenatal Detection of Small-for-Gestational-Age Infants in a UK National Health Service Trust

英国国家医疗服务体系信托机构对产前筛查小于胎龄儿的服务评估

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Abstract

Introduction Infants with a birthweight below the 10th centile are classified as small-for-gestational age (SGA). SGA is closely associated with fetal growth restriction (FGR), and both represent significant risk factors for stillbirth. The UK continues to report comparatively high stillbirth rates, and antenatal detection of SGA is a recognised strategy for reducing this risk. This service evaluation assessed the antenatal detection rate of SGA infants at Mid Yorkshire Hospitals NHS Trust (MYHT). Methods This was a retrospective observational cohort service evaluation conducted between January and March 2020 using total-population sampling of all eligible cases. Using the BadgerNet maternity system, 124 SGA infants were identified, of which 110 were included after applying eligibility criteria. Data were collected on 12 potential risk factors, including maternal age, medical comorbidities, and history of SGA births. The overall detection rate for the Trust was calculated, and a multivariable (binary) logistic regression was performed using IBM SPSS Statistics for Windows, Version 26 (Released 2019; IBM Corp., Armonk, New York, United States) following descriptive analysis in Microsoft Excel. Missing data were addressed using multiple imputation, and supplementary analyses were conducted for contextual understanding. Results A total of 42.7% of SGA infants were detected in the antenatal period; 97.9% of these were identified following referral for an abnormal symphyseal fundal height (SFH) measurement. The regression model was statistically significant, χ²(12) = 47.7-50.9, p < 0.001. Maternal smoking was associated with a 3.9-fold increase in detection (95% CI, 1.01-14.9), while referral after an abnormal SFH measurement increased the likelihood of detection by 154-fold (95% CI, 14.9-1603.4). Conclusions The antenatal detection rate of SGA infants at MYHT mirrors the national average, yet most cases remain undetected across the UK. Detection was primarily driven by referral after abnormal SFH measurements, underscoring the value of routine screening. Maternal smoking also independently increased detection, reflecting its strong association with fetal growth restriction. National adoption of customised centiles in systems such as BadgerNet may improve alignment with clinical practice, support earlier recognition of at-risk pregnancies, and contribute to reducing stillbirth rates.

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