Abstract
Medication-induced pulmonary toxicity is a rare adverse event that may occur with many chemotherapeutic agents, including etoposide. This agent has been found to cause various toxicities, including anaphylaxis, angioedema, hypotension, and pneumonitis. Etoposide is used in chemotherapy regimens for multiple cancers, including germ-cell tumors. Proper diagnosis of chemotherapy-induced pulmonary toxicity is imperative and should be considered in patients who develop acute respiratory failure during or after chemotherapy. Here, we discuss an unexpected case of etoposide-induced pneumonitis after a short course of IV etoposide in a patient with metastatic seminoma.