Phenotyping fatty acids and the trans-10 shift in the rumen content and adipose tissue of commercial finishing lambs

商业育肥羔羊瘤胃内容物和脂肪组织中脂肪酸表型及反式-10脂肪酸变化

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Abstract

The trans-10 shifted ruminal biohydrogenation (BH) of unsaturated fatty acids (FA) pathways is characterised by the replacement of trans-11 18:1 by trans-10 18:1 as the predominant ruminal BH intermediate. The t10-shift occurs frequently in animals kept in intensive feeding systems and affects the nutritional quality of ruminant-derived foods. This study aimed to phenotype the prevalence and variability of the t10-shift in a large population of finishing lambs and to relate it to rumen fermentation parameters, microbial lipid markers, and adipose tissue FA. A total of 630 lambs from seven genetic groups were finished in a lamb finishing unit on a high-concentrate diet. The sampling covered 11 collection occasions at the slaughterhouse between 2022 and 2024. Rumen digesta, collected post-mortem, were analysed for volatile fatty acids (VFA), long-chain FA, and dimethyl acetals (DMA), while kidney knob channel fat (KKCF) was analysed in a subset of animals (n = 111). The t10-shift ratio (t10-18:1/t11-18:1) in the rumen content was >1 for 89% of the animals. Significant genetic group effects were observed for rumen pH, VFA, DMA, and FA composition, including C18 intermediates. Trans-10 18:1 and t10-shift ratio were negatively correlated with rumen pH and 18:0, indicating more incomplete ruminal BH pathways under acidic conditions. In KKCF, differences in trans-18:1 isomers were detected among groups, and rumen t10-18:1 and t11-18:1 were positively associated with the deposition of t10-18:1 and t11-18:1 + c9t11-18:2 in adipose tissue, respectively. Notably, a minority of animals appeared resistant to the t10-shift despite standardised finishing conditions, highlighting potential for genetic selection.

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