Bone marrow aspirate concentrate adjunct for acetabular labral tear repair: a systematic review and meta-analysis

骨髓抽吸物浓缩液辅助治疗髋臼盂唇撕裂:系统评价和荟萃分析

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Abstract

BACKGROUND: The objective of this study was to determine the effect of bone marrow aspirate concentrate (BMAC) on long-term patient outcomes when used as an adjuvant to acetabular repair of the labrum. METHODS: A systematic review and meta-analysis were completed following PRISMA 2020 guidelines. Included in the analysis were controlled studies which assessed functional outcomes via the International Hip Outcome Tool-33 (iHOT-33) 12 or 24 months after acetabular repair with BMAC adjunct. 4 studies totaling 315 participants were analysed. RESULTS: Pooled effect sizes for iHOT-33 scores were not significantly different between control and treatment groups at 12 (p = 0.14, Cohen's D ≏ 0.79) or 24 months (p = 0.30, Cohen's D ≏ 0.56). CONCLUSIONS: Non-significant trends in favour of BMAC augmentation were found in this study. However, the trends reported are promising and warrant further investigation with further randomised controlled trials.

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