Infective Endocarditis and Septic Emboli: Diagnostic Delays, Implications, and Challenges

感染性心内膜炎和脓毒性栓塞:诊断延误、影响和挑战

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Abstract

Infective endocarditis (IE) presents significant diagnostic challenges and needs a high index of clinical suspicion. This study describes a case illustrating these complexities. A 69-year-old woman initially presented with confusion and expressive dysphasia, following five days of treatment for left-sided otitis media. Further investigations revealed evidence of Streptococcus infection. The patient was diagnosed with pneumococcal infective endocarditis, complicated by intracranial septic emboli and multiorgan failure. This resulted in prolonged hospital stay and the development of multi-morbidity and increased frailty index. IE was diagnosed only upon readmission, leading to delays in treatment. This study underscores the importance of early suspicion and repeat investigations in IE. Evolving diagnostic criteria emphasize a multidisciplinary approach to managing these life-threatening conditions.

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