Abstract
This editorial addresses the urgent and multifaceted issue of zero-dose children - those who have not received any routine vaccinations, such as for measles, diphtheria, or polio. These children are predominantly found in marginalized communities, conflict zones, and areas with limited healthcare infrastructure. The rise in zero-dose cases is driven by a combination of misinformation, vaccine hesitancy, poverty, geographic inaccessibility, gender-based barriers, and historical mistrust in healthcare systems. The recent resurgence of vaccine-preventable diseases highlights the need for immediate and collaborative action. The authors advocate for integrated solutions, including the engagement of community and religious leaders, digital platform accountability, and inclusive public health policies. Successful case studies - such as France and Italy's mandatory vaccination laws, Brazil's Bolsa Família program, and mobile health initiatives - demonstrate effective pathways to increase vaccine coverage. Rebuilding trust through culturally sensitive education, transparency, and improved access to immunization services is essential to ensure that no child is left behind.