Abstract
INTRODUCTION: Transvaginal mesh surgery (TVM) is a less invasive and time-efficient surgical technique for the treatment of pelvic organ prolapse (POP). However, POP recurrence is a concern in patients treated with TVM using the ORIHIME (Kono Seisakusho, Japan, Tokyo) mesh. In this study, we investigated the influence of mesh-related factors on POP recurrence after TVM using ORIHIME. METHODS: The study enrolled 104 patients who underwent TVM at our hospital between July 2019 and March 2024. The Pearson chi-squared test, multiple logistic regression analysis, and Cox proportional hazards model were used to identify independent predictors of prolapse recurrence. RESULTS: Among preoperative and intraoperative factors, POP stage 4 and mesh arm width < 6 cm were significantly associated with prolapse recurrence (both p <0.05). On multiple logistic regression analysis, only the mesh arm width < 6 cm was a significant predictor of recurrence (p = 0.0077). Additionally, in the multivariate Cox proportional hazards model, only the mesh arm width < 6 cm was an independent predictor of shorter time to prolapse recurrence (hazard ratio, 8.39; 95% confidence interval, 1.70 - 41.35; p = 0.0089). CONCLUSION: Narrow mesh arm width can contribute to POP recurrence after TVM using ORIHIME. Applying wider mesh arms can help minimize the POP recurrence rate.