N,N-Dimethylformamide's Participation in Domino Reactions for the Synthesis of Se-Phenyl Dimethylcarbamoselenoate Derivatives

N,N-二甲基甲酰胺参与多米诺反应合成硒苯基二甲基氨基甲烯酸酯衍生物

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Abstract

N,N-dimethylformamide's (DMF) participation in domino reactions has been developed. Starting from substituted halogenobenzenes and selenium powder, versatile biologically active Se-phenyl dimethylcarbamoselenoate derivatives were efficiently synthesized under mild reaction conditions. The reaction mechanism was studied using control experiments. These protocols involve a wider substrate scope and provide an economical approach toward C-selenium bond formation.

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