Abstract
May-Thurner Syndrome (MTS) is caused by left common iliac vein compression, resulting in deep vein thrombosis (DVT). MTS is usually asymptomatic until DVT occurs. Our case features a 37-year-old woman who presented with swelling and pain in her left leg after recent travel and oral contraceptive use. Venous duplex ultrasound confirmed DVT and CT angiogram excluded pulmonary embolism. She received Heparin anticoagulation and underwent mechanical thrombectomy and stenting. Her symptoms improved within two days, and she was discharged on Apixaban and Plavix. This case involves a unique patient presentation of MTS, involving young woman with unexplained left-sided DVT, a scenario typically seen in older patients with clotting disorders.