Abstract
Streptococcus pneumoniae is a pathogenic bacterium that causes invasive pneumococcal disease in humans, especially pediatric patients. Antibiotics are primary therapeutic agents. Resistance to antibiotics is a growing health problem, and healthcare authorities have warned that 10 million people will die each year by 2050 and become the first killer. To date, resistance to vancomycin has not been recorded in Iraq. This study reports a 9-month-old infant presented with fever, irritability, crying, and decreased oral intake for 3 days. Cerebrospinal fluid (CSF) parameters included turbid appearance, pleocytosis, and high protein and low sugar levels. Culture and sensitivity tests revealed the growth of Streptococcus pneumoniae, which is resistant to vancomycin. Reporting vancomycin resistance in Streptococcus pneumonia adds to the growing body of research on the pandemic of drug resistance. It indicates when all antibiotics are ineffective, as in the pre-antibiotic era, and this needs a more comprehensive plan.