Abstract
Oral diseases remain a pressing global health challenge, affecting billions and disproportionately affecting underserved and vulnerable populations. Despite strong evidence supporting preventive measures, this evidence often fails to translate into real-world practice due to fragmented health systems, a treatment-dominated model of dental care, and a lack of focus on upstream, population-wide prevention strategies. Implementation research helps to bridge the effectiveness-implementation gap by systematically studying how interventions can be integrated into real-world settings and sustained effectively. Implementation research requires a multidisciplinary approach that often goes beyond traditional research settings, prioritizing stakeholder engagement, local context, and iterative testing and aligning interventions with community needs. To support the design and evaluation of these implementation efforts, logic models are practical tools that can be used to help map determinants, strategies, and outcomes using underlying causal reasoning. Once determinants have been identified, trials can be developed to incorporate implementation outcomes such as acceptability (how agreeable it is among stakeholders), adoption (the uptake), and fidelity (how closely implemented as intended), providing insights into the real-world performance of interventions. Implementation strategies should be clearly defined and documented by detailing their rationale, specific actions, and outcomes they are intended to affect. Specifying and contextualizing strategies in this way ensures they can be appropriately evaluated. This article identifies 3 examples that show the importance of embedding interventions within existing health systems and policies and how bottom-up approaches, such as engaging stakeholders from the outset, are critical to the success of the implementation. Integrating implementation considerations early in the research process and fostering strategic partnerships between research organizations, policymakers, and communities are essential to translating evidence into meaningful oral health improvements and bridging the gap between research and real-world impact.