Abstract
Eosinophilic colitis (EC) is a rare subtype of eosinophilic gastrointestinal disorders, marked by dense eosinophilic infiltration of the colon in the absence of secondary causes. We report the case of a 48-year-old Ethiopian man with a history of atopic disease who presented with chronic nonbloody diarrhea, intermittent abdominal pain, and fatigue. Diagnostic colonoscopy with biopsy confirmed EC, supported by peripheral eosinophilia and histological findings. The patient was treated with oral prednisolone, leading to complete symptom resolution.