Case Series of a Previously Undescribed Ulcerative Variant of Hidradenitis Suppurativa

化脓性汗腺炎溃疡变异型病例系列研究(此前未曾描述)

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Abstract

INTRODUCTION: Hidradenitis suppurativa (HS) is an auto-inflammatory disease characterized by recurrent painful nodules, abscesses, tunnels, and scarring, commonly seen in intertriginous body surfaces; however, an additional ulcerative phenotype has not been described and represents a specific clinical phenotype of the disease requiring special therapeutic considerations. CASE PRESENTATION: We report 4 patients with a previously undescribed, ulcerative phenotype of HS that did not respond to standard treatment but were healed with surgery. These lesions present as large, deep-dermal, erythematous, well-defined ulcers that are exquisitely tender. CONCLUSION: This phenotype necessitates recognition by the clinician as a rapid path to combined pharmacologic and surgical management is crucial for the patient.

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